Synthesis of symmetrical trisubstituted olefins by cross metathesis

AK Chatterjee, DP Sanders, RH Grubbs

Index: Chatterjee, Arnab K.; Sanders, Daniel P.; Grubbs, Robert H. Organic Letters, 2002 , vol. 4, # 11 p. 1939 - 1942

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Citation Number: 149

Abstract

Trisubstituted alkenes have been prepared via intermolecular olefin cross-metathesis (CM) between α-olefins and symmetrically 1, 1-disubstituted olefins using an imidazolylidene ruthenium benzylidene complex. Of particular interest is the synthesis of isoprenoid/prenyl groups by a simple solvent-free CM reaction with isobutylene. In addition, prenyl groups can also be installed by a cross-metathesis of 2-methyl-2-butene with a variety of α-olefins at ...