Tetrahedron letters

First report of a permanent open form of a naphthopyran

…, PJ Coelho, LM Carvalho, AMF Oliveira-Campos

Index: Martins, Cristina I.; Coelho, Paulo J.; Carvalho, Luis M.; Oliveira-Campos, Ana M.F. Tetrahedron Letters, 2002 , vol. 43, # 12 p. 2203 - 2205

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Citation Number: 11

Abstract

The synthesis of a permanent open form of a naphthopyran is described for the first time. The open form of the 10-hydroxy-2H-naphtho [1, 2-b] pyran, obtained by reaction of 1, 8- dihydroxy-naphthalene with 1, 1-diphenylprop-2-yn-1-ol under acid catalysis, is stable due to the establishment of an intramolecular hydrogen bond.