Synthesis of diphenic acid derivatives

WD Roll, GE Cwalina

Index: Roll,W.D.; Cwalina,G.E. Journal of Pharmaceutical Sciences, 1962 , vol. 51, p. 941 - 944

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Abstract

Abstract Five new derivatives of diphenic acid were prepared for the purpose of studying their antibacterial, antihyperglycemic, antispasmodic, and/or local anesthetic activity: o, o′- bis (2-nitro-1, 3-dihydroxypropyl) biphenyl disodium salt; o, o′-bis (3-benzoxy-2-benzamido- 1-hydroxypropyl) biphenyl; o, o′-bis (β-dichloroacetamidoethyl) diphenate; N, N′-bis (benzenesulfonyl)-o, o′-diphenoylurea, and m, m′-bis (Ncarboxymethyl) diphenamide.