Eco-friendly synthesis of 2-substituted-2, 3-dihydro-4 (1H)-quinazolinones in water

M Wang, TT Zhang, ZG Song

Index: Wang, Min; Zhang, Ting Ting; Song, Zhi Guo Chinese Chemical Letters, 2011 , vol. 22, # 4 p. 427 - 430

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Citation Number: 41

Abstract

2-Substituted-2, 3-dihydro-4 (1H)-quinazolinones were synthesized in high yield by condensation of 2-anthranilamide with aromatic aldehydes or ketones in refluxing water without catalyst. This protocol has advantages of high yield, simple work-up and environmental friendly procedure.