Synthetic Communications

Conjugate addition-decarboxylation of magnesium monoethyl malonate to enones: A convenient one-flask addition of acetate

JE Mcmurry, WA Andrus, JH Musser

Index: McMurry,J. et al. Synthetic Communications, 1978 , vol. 8, # 1 p. 53 - 57

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Citation Number: 18

Abstract

Abstract We described recently1 an improved procedure for carrying out the malonic ester synthesis whereby alkylation and decarboxylation occur in a single pot. This is accomplished by alkylating the dilithio salt of monoethyl malonic acid and then warming the resultant product.

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