Synlett

Combinatorial synthesis of carbohydrate cluster on tree-type linker with orthogonally cleavable parts

T Amaya, H Tanaka, T Takahashi

Index: Amaya, Toru; Tanaka, Hiroshi; Takahashi, Takashi Synlett, 2004 , # 3 p. 497 - 502

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Citation Number: 7

Abstract

Abstract We have successfully developed a synthetic strategy for the combinatorial solid- phase synthesis of carbohydrate clusters on a tree-type linker with two types of orthogonally cleavable parts. The combination of three types of spacers, two types of carbohydrate ligands, and two types of orthogonal cleavage provided a 12-member carbohydrate cluster library (6 dimers and 6 tetramers).