Journal of the American Chemical Society

A new route to functionalized trans-hydrindenones

BB Snider, TC Kirk

Index: Snider,B.B.; Kirk,T.C. Journal of the American Chemical Society, 1983 , vol. 105, p. 2364

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Citation Number: 40

Abstract

Abstract: MeA1C12-initiated cyclization of dienone 12 provides the functionalized trans- fused hydrindenone 15 in 50% yield. Ketone 15, which is now readily available in three steps from hydrocinnamic acid via this novel cyclopentanone synthesis, has been converted to 27 and 30, thus completing a formal total synthesis of 1 I-oxo steroids.

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