Oxidative decyanation of secondary nitriles to ketones

RW Freerksen, SJ Selikson, RR Wroble…

Index: Freerksen, Robert W.; Selikson, Sandra J.; Wroble, Randall R.; Kyler, S. Keith; Watt, David S. Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4087 - 4096

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Citation Number: 49

Abstract

Procedures for the oxidative decyanation of secondary nitriles to ketones involve (1) iodination of N-(trialkylsily1) ketenimines derived from secondary nitriles and subsequent hydrolysis of the dodo nitriles with silver oxide,(2) addition of nitrosobenzene to N- (trialkylsilyl) ketenimines,(3) conversion of secondary nitriles to a-(phenylthio) nitriles and subsequent hydrolysis with N-bromosuccinimide in aqueous acetonitrile, and (4) ...