Advanced Synthesis & Catalysis

Enzymatic synthesis of chiral phenylalanine derivatives by a dynamic kinetic resolution of corresponding amide and nitrile substrates with a multi??enzyme system

K Yasukawa, Y Asano

Index: Advanced Synthesis and Catalysis, , vol. 354, # 17 p. 3327 - 3332

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Citation Number: 24

Abstract

... Issue. Advanced Synthesis & Catalysis. ... The non-natural amino acid known as (S)-2l is an important chiral intermediate to synthesize a variety of pharmaceuticals ... Synthesis of (R)-2e from (RS)-2-Aminophenyl- propionitrile using Nitrile Hydratase and E. coli pACLmut/pDBFB40. ...

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