On the [2+ 2] cycloaddition of 2-aminothiazoles and dimethyl acetylenedicarboxylate. Experimental and computational evidence of a thermal disrotatory ring opening …

…, J Cabrera, A Pastor, P Sánchez-Andrada…

Index: Birkinshaw, Timothy N.; Meakins, G. Denis; Plackett, Simon J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2209 - 2212

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Citation Number: 31

Abstract

... J. Org. Chem. ... 6, 5f, 25, 6 d, f, 80, 0. 7, 5g, 25, 12, g, 85, 0. ... 11 The simultaneous formation of pyridines 6j (32%) and 6k (40%) was rationalized in terms of a [1,3]-shift of the Me 2 N group in the initial [4 + 2] adduct 11, followed by elimination of Me 2 NH or MeSH from the intermediate ...