Molecular editing and biological evaluation of amphidinolide X and Y
A Fürstner, E Kattnig, G Kelter…
Index: Fuerstner, Alois; Kattnig, Egmont; Kelter, Gerhard; Fiebig, Heinz-Herbert Chemistry - A European Journal, 2009 , vol. 15, # 16 p. 4030 - 4043
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Citation Number: 25
Abstract
Abstract Scarce and precious: A collection of compounds with deep-seated structural “point mutations” within the framework of the marine natural products amphidinolide X and Y was prepared by “diverted total synthesis”. The resulting products provided first insights into the cytotoxicity profile of these extremely scarce macrolides.
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