FK041, a novel orally active cephalosporin: synthesis and biological properties.

…, K Kawabata, S Tawara, H Takasugi, H Tanaka

Index: Yamamoto; Kawabata; Tawara; Takasugi; Tanaka Journal of Antibiotics, 1998 , vol. 51, # 7 p. 683 - 687

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Citation Number: 7

Abstract

Recently, new oral cephalosporins with broad spectra of activity and high stability against various β-lactamases, such as cefixime1)(CFIX), ceftibutene2)(CFTB), and cefdinir3)(CFDN), have been developed and introduced to clinical practice. In particular, CFDN, which was discovered in our laboratories, has excellent antibacterial activity against both Gram-positive and-negative bacteria and high oral absorption. 3) CFDN has shown excellent clinical ...