Synthesis of biologically important novel fluorinated spiro heterocycles under microwaves catalyzed by montmorillonite KSF

K Arya, A Dandia

Index: Arya, Kapil; Dandia, Anshu Journal of Fluorine Chemistry, 2007 , vol. 128, # 3 p. 224 - 231

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Citation Number: 32

Abstract

The arylidienes of fluorinated spiro thiazolidines (5) containing α, β-unsaturated function have been used as component of Micheal addition with equimolar amount of 2- aminopyridine (6a) to give novel fluorinated spiro [indole-3, 2′-pyrido [1, 2-a] thiazolo [5, 4- e] pyrimidines](7) in a single step under microwaves in presence of montmorillonite KSF as solid support. The new improved synthetic method for fluorinated spiro [indole-3, 2′- ...