Efficient routes to pyrazolo [3, 4-e][1, 2, 4] triazines and a new ring system:[1, 2, 4] triazino [5, 6-d][1, 2, 3] triazines

HM Al-Matar, KD Khalil, DM Al-Dorri, MH Elnagdi

Index: Al-Matar, Hamad Mohamed; Khalil, Khaled Dessouky; Al-Dorri, Doa'A Mohamed; Elnagdi, Mohamed Helmy Molecules, 2010 , vol. 15, # 5 p. 3302 - 3310

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Citation Number: 7

Abstract

Abstract Arylhydrazonomalononitriles 1a, b react with phenylhydrazine to yield amidrazones 2a, b that cyclize to give 2-aryl-5-phenylhydrazono-2, 5-dihydro-[1, 2, 4]-triazine-6- carbonitriles 5a, b upon reaction with dimethylformamide dimethylacetal (DMFDMA). Refluxing 5a, b in glacial acetic acid resulted in the formation of the pyrazolo-1, 2, 4-triazines 6a, b. Compounds 6a, b were also formed upon treatment of 3-amino-4-phenylhydrazono- ...