Metal-promoted cyclization. 25. Palladium-catalyzed cascade carbometalation of alkynes and alkenes as an efficient route to cyclic and polycyclic structures

Y Zhang, E Negishi

Index: Zhang, Yantao; Negishi, Ei-ichi Journal of the American Chemical Society, 1989 , vol. 111, # 9 p. 3454 - 3456

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Citation Number: 141

Abstract

18 (76%) reochemical assignments were made based on a combination of'H and 13C NMR as well as' H 2D NOESY NMR. Having achieved the intramolecular-intermolecular cascade carbopalladation described above, we then considered the intramolecular-intramolecular cascade carbopalladation of the following two types. A similar cascade involving alkenes was recently reported by Overman. Io As indicated by the high yield conversions of 13-15 ...