Tetrahedron

Synthesis of 2, 4-diacetylthiazole and 2, 5-diacetylthiazole

KM Aitken, RA Aitken

Index: Aitken, Kati M.; Aitken, R. Alan Tetrahedron, 2008 , vol. 64, # 19 p. 4384 - 4386

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Citation Number: 14

Abstract

Simple acetylated nitrogen and sulfur-containing heterocycles occur in many cooked foodstuffs and are of current interest to the food industry as flavour and aroma ingredients. For example, 2-acetylthiazole 1 was detected in the 1970s in cooked and canned beef, 1 and 2 cooked pork liver, 3 cooked potato 4 and rice bran. 5 More recently, the same compound has been found to be formed from the garlic constituent alliin both by thermal degradation in acidic ...