The Journal of organic chemistry

Aromatization of 1, 6, 7, 7a-Tetrahydro-2 H-indol-2-ones by a Novel Process. Preparation of Key-Intermediate Methyl 1-Benzyl-5-methoxy-1 H-indole-3-acetate and …

G Revial, I Jabin, S Lim, M Pfau

Index: Pfau,M.; Ribiere,C. Bulletin de la Societe Chimique de France, 1971 , p. 2584 - 2590

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Citation Number: 25

Abstract

Imine 7 of 1, 4-cyclohexanedione mono-ethylene ketal 6 was reacted with maleic anhydride, affording the cyclized adduct 8. Methyl esterification of 8, accompanied by transacetalization, led to the dihydrooxindole derivative 10. Aromatization of 10 was then accomplished with

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