Synthesis of arylated highly congested indans using a domino sequence

R Pratap, B Kumar, VJ Ram

Index: Pratap, Ramendra; Kumar, Brijesh; Ram, Vishnu Ji Tetrahedron, 2007 , vol. 63, # 41 p. 10300 - 10308

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Citation Number: 7

Abstract

A novel and efficient regioselective synthesis of various arylated highly congested 7-aryl-5- methylsulfanylindan-4-carbonitriles (3a–f), methyl 7-aryl-5-methylsulfanylindan-4- carboxylates (10a–e) and 7-aryl-5-methylsulfanylindan-4-carboxylic acids (11a–e) through base-catalyzed reaction of 6-aryl-4-methylsulfanyl-2-oxo-2H-pyran-3-carbonitriles (1a–f) and methyl 6-aryl-4-methylsulfanyl-2-oxo-2H-pyran-3-carboxylates (9a–e) by ...