Simple syntheses of diethyl oxomalonate and alkyl glyoxylates

ME Jung, K Shishido, LH Davis

Index: Jung, Michael E.; Shishido, Kozo; Davis, Leonard H. Journal of Organic Chemistry, 1982 , vol. 47, # 5 p. 891 - 892

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Citation Number: 45

Abstract

Diethyl oxomalonate (1) and ethyl, methyl, and benzyl glyoxylates (2a, b, c) are useful reagents in organic chemistry. The a-keto ester functionality of all of these compounds is quite reactive and participates in electrocyclic processes (Diels-Alder reaction: ene reaction3) and various condensations (ald~ l,~ carbinolamine f~ rmation,~ Friedel-Crafts reaction, 6 and Wittig reaction2e). Recently several new methods have been developed ...

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