The Journal of Organic Chemistry

A stereospecific synthesis of 3, 3-disubstituted allylic alcohols. The intermolecular pinacol cross-coupling reaction between. alpha.,. alpha.-disubstituted. alpha.-( …

J Park, SF Pedersen

Index: Park, Jeonghan; Pedersen, Steven F. Journal of Organic Chemistry, 1990 , vol. 55, # 24 p. 5924 - 5926

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Citation Number: 44

Abstract

Summary: High diastereofacial selectivity is observed in the intermolecular pinacol cross- coupling of a, a-disubstituted a-(diphenylphosphinoy1) acetaldehydes with saturated aldehydes. The diols obtained from these reactions are converted to (E)-allylic alcohols via a Horner-Wittig elimination reaction.

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