Difunctionalized trans-2, 5-disubstituted pyrrolidine (azethoxyl) nitroxide spin-labels

…, SE Seyedrezai, G Gaughan

Index: Keana, John F. W.; Seyedrezai, Seyed E.; Gaughan, Glen Journal of Organic Chemistry, 1983 , vol. 48, # 16 p. 2644 - 2647

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Citation Number: 22

Abstract

The synthesis of two short-chain trans-2, 5-difunctionalized azethoxyl nitroxide spin-labels, dinitrile 12 and dicarboxylic acid 14, is described. The trans stereochemistry of 12 and 14 was established by conversion of 12 to a diastereomeric mixture of N-hydroxy esters 13, which was analyzed by NMR spectroscopy.

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