0Oxidative Bromination of Activated Aromatic Compounds Using Aqueous Nitric Acid as an Oxidant

…, S Mukhopadhyay, Y Sasson

Index: Joshi, Ashutosh V.; Baidoosi, Mubeen; Mukhopadhyay, Sudip; Sasson, Yoel Organic Process Research and Development, 2003 , vol. 7, # 1 p. 95 - 97

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Citation Number: 33

Abstract

Oxidative bromination of activated aromatic compounds using alkali metal bromide salts and aqueous nitric acid to the corresponding bromo-derivatives is achieved in a liquid-liquid, two- phase system under ambient conditions. Nitric acid offers a dual function of an oxidant as well as a proton donor, which is essential for oxidative bromination using metal bromide salts. Bromination as well as chlorination could be accomplished with this simple system.