Novel use of substituted 1, 4-dihydrobenz [d][1, 3] oxazin-2-ones in the synthesis of important aminomethyl o-nitroanilines

…, BE Kornberg, B Tobias, MF Rafferty

Index: Nikam, Sham S.; Kornberg, Brian E.; Rafferty, Michael F. Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3754 - 3757

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Citation Number: 7

Abstract

Multifunctional o-nitroanilines are important intermediates in the synthesis of a variety of nitrogen heterocycles. 1 However, there are very few efficient methods to synthesize heteroalkyl side chains ortho to the amino group, which give the corresponding peri position substitution in the resultant nitrogen heterocycle. Earlier, we standardized a novel method for the synthesis of benzylamine derivatives 2 with an aminomethyl side chain ortho to the ...