Tributylphosphine-catalyzed acylations of alcohols: scope and related reactions

E Vedejs, NS Bennett, LM Conn, ST Diver…

Index: Vedejs, E.; Bennett, N. S.; Conn, L. M.; Diver, S. T.; Gingras, M.; et al. Journal of Organic Chemistry, 1993 , vol. 58, # 25 p. 7286 - 7288

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Citation Number: 211

Abstract

Recent findings in our laboratory show that tributylphosphine is a potent catalyst for the acylation of representative alcohols by acetic or benzoic anhydrides. 1 Acylations using excess anhydride and 5-20 mol 5% of Bu3 catalyst in benzene or acetonitrile are comparable in rate to the analogous reactions catalyzed byp (dimethylamin0)-pyridine (DMAP). l*% In the case of benzoic anhydride, the BQP-catalyzed reaction is faster than ...