Convenient method for the stereoselective synthesis of 3-phenyl-1-alkynes

AM Caporusso, C Polizzi, L Lardicci

Index: Caporusso, Anna Maria; Polizzi, Carmela; Lardicci, Luciano Journal of Organic Chemistry, 1987 , vol. 52, # 17 p. 3920 - 3923

Full Text: HTML

Citation Number: 32

Abstract

General Procedures for the Preparation of a-Iodo Ketones from Enol Silyl Ethers. To a solution of enol silyl ether (1" 01) and sodium iodide (1.1 mmol) in THF (10 mL) was added dropwise a solution of MCPBA (1.2 mmol) in dry &chloromethane (3 mL) at 0" C. The reaction mixture was stirred for 5 min, then diluted with ether (50 mL), and washed with 10% hydrochloric acid (10 mL), saturated sodium thiosulfate (10 mL), saturated sodium ...