Tetrahedron

Inverse Phase Transfer Catalysis. III.-Optimization of the epoxidation reaction of α, β-unsaturated ketones by hydrogen peroxide

B Boyer, A Hambardzoumian, JP Roque, N Beylerian

Index: Boyer, Bernard; Hambardzoumian, Araik; Roque, Jean-Pierre; Beylerian, Norair Tetrahedron, 1999 ,  vol. 55,  # 19  p. 6147 - 6152

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Citation Number: 27

Abstract

The epoxidation of chalcone using hydrogen peroxide in the presence of a base in a two- phase medium system following the so-called Inverse Phase Transfer Catalysis (IPTC) process was investigated. Careful examination of various parameters including surfactant concentration, pH, H2O2 decomposition side-reactions and epoxide ring-opening, allowed us to determine optimal experimental conditions