Selective monofluorination of. beta.-diketones

…, CL Bumgardner, NV Lazaridis, P Singh

Index: Purrington, Suzanne T.; Bumgardner, Carl L.; Lazaridis, Nicholas V.; Singh, Phirtu Journal of Organic Chemistry, 1987 ,  vol. 52,  # 19  p. 4307 - 4310

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Citation Number: 48

Abstract

Results Since the reagents used for fluorination of P-diketones are either expensive or explosive, investigation of the use of dilute fluorine was undertaken. Recently, we have found that trimethylsilyl enol ethers can be selectively fluorinated to give a-fluoro ketones using dilute fl~ orine.~ Since trimethylsilyl enol ethers of p-diketones are readily formed'O as indicated in eq 1, their fluorination was iii ii PSIMes