A new versatile synthesis of 2, 5-disubstituted 3-(methylsulfanyl) thiophenes

…, E Cadoni, MG Cabiddu, S De Montis, S Cabiddu

Index: Fattuoni, Claudia; Usai, Michele; Cadoni, Enzo; Cabiddu, M. Grazia; De Montis, Stefania; Cabiddu, Salvatore Synthesis, 2008 , # 6 p. 985 - 989

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Abstract

Abstract A one-pot regioselective functionalization of 3-(methylsulfanyl) thiophene with different electrophiles at the 2-and 5-positions is reported. Proper selection of the experimental conditions allows the preparation of polysubstituted products not otherwise easily available.

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