Substituted (pyridylmethoxy) naphthalenes as potent and orally active 5-lipoxygenase inhibitors: Synthesis, biological profile, and pharmacokinetics of L-739,010

P Hamel, D Riendeau, C Brideau…

Index: Journal of Medicinal Chemistry, , vol. 40, # 18 p. 2866 - 2875

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Citation Number: 33

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The pyridine-containing final products 3a−d,g were obtained via Mitsunobu-type condensations of pyridinemethanols 4a−e with the cyanonaphthalene phenol 7 5 (Table ...

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