Chemical and Pharmaceutical Bulletin

Thermal Cyclization of Nonconjugated Aryl-Yne-Carbodiimide Furnishing a Dibenzonaphthyridine Derivative

H Kimura, K Torikai, I Ueda

Index: Kimura, Hidenori; Torikai, Kohei; Ueda, Ikuo Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 4 p. 393 - 396

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Citation Number: 5

Abstract

The reagent-free C 2–C 7 thermal cyclization of a nonconjugated aryl–yne–carbodiimide yielded a dibenzo [b, g][1, 8] naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of “nonconjugated” aryl–ynes.