Highly enantioselective recombinant thermoalkalophilic lipases from Geobacillus and Bacillus sp

…, L Hunter, N Ehya, MD Gibbs, PL Bergquist…

Index: Hutchins, Lauren M.; Hunter, Luke; Ehya, Noosha; Gibbs, Moreland D.; Bergquist, Peter L.; Hutton, Craig A. Tetrahedron Asymmetry, 2004 , vol. 15, # 18 p. 2975 - 2980

Full Text: HTML

Citation Number: 7

Abstract

Thermoalkalophilic lipases from Geobacillus and Bacillus strains have been cloned and characterised, several of which show excellent activity and enantioselectivity towards various substrates. The hydrolysis of methyl 2-methyldecanoate proceeds to give (R)-2- methyldecanoic acid in good yield and> 99% enantiomeric excess (E> 200).

Related Articles:

Highly Regioselective Anti-Markovnikov Palladium-Borate-Catalyzed Methoxycarbonylation Reactions: Unprecedented Results for Aryl Olefins

[Vieira, Tiago O.; Green, Mike J.; Alper, Howard Organic Letters, 2006 , vol. 8, # 26 p. 6143 - 6145]

Novel fatty acid methyl esters from the actinomycete Micromonospora aurantiaca

[Dickschat, Jeroen S.; Bruns, Hilke; Riclea, Ramona Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 1697 - 1712]

Selective Mono-and Bis (alkoxycarbonylation) s of Olefins Catalyzed by Palladium in the Presence of Cu (I) or Cu (II) Chloride under Remarkably Mild Conditions. …

[Toda, Shiho; Miyamoto, Masanori; Kinoshita, Hideki; Inomata, Katsuhiko Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 12 p. 3600 - 3606]

Volatile methyl esters of medium chain length from the bacterium Chitinophaga Fx7914

[Nawrath, Thorben; Gerth, Klaus; Mueller, Rolf; Schulz, Stefan Chemistry and Biodiversity, 2010 , vol. 7, # 9 p. 2228 - 2253]

Addition of Carboxyalkyl Radicals to Alkenes through a Catalytic Process, Using a Mn (II)/Co (II)/O2 Redox System

[Hirase, Koji; Sakaguchi, Satoshi; Ishii, Yasutaka Journal of Organic Chemistry, 2003 , vol. 68, # 15 p. 5974 - 5976]

More Articles...