Scope and mechanism of allylic C− H amination of terminal alkenes by the palladium/PhI (OPiv) 2 catalyst system: Insights into the effect of naphthoquinone

G Yin, Y Wu, G Liu

Index: Yin, Guoyin; Wu, Yichen; Liu, Guosheng Journal of the American Chemical Society, 2010 , vol. 132, # 34 p. 11978 - 11987

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Citation Number: 117

Abstract

Palladium-catalyzed oxidative amination of unactivated alkyl olefins has been developed to produce linear (E)-allylimides with high regioselectivity. This highly efficient transformation of alkenes has been achieved by enhancing the reoxidation of palladium with the strong oxidant PhI (OPiv) 2. The present work also provides the first systematic analysis of the mechanism of the allylic C− H oxidative amination. It has been found that naphthoquinone ...