Studies on Methylglyoxal Bis (guanylhydrazone) 1 Analogs. II. Structural Variations on Methylglyoxal Bis (guanylhydrazone) 2

F Baiocchi, CC Cheng, WJ Haggerty Jr…

Index: Baiocchi,F. et al. J. Med. Chem., 1963 , vol. 6, p. 431 - 435

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Citation Number: 41

Abstract

A study of analogs of methylglyoxal bis (guany1hydrazone) was conducted. Structural modifications of the parent compound, all containing the fundamental> C= N-NH-C (= SH) NH- moiety, are divided into 9 different classes. These modifications include the substitution of the methyl group, substitution of the hydrogen atom attached to the aldimine carbon, separation of the two guanidoimino and guanylhydrazonyl groups by various aliphatic ...