A selective and convenient ruthenium mediated method for the synthesis of mixed acetals and orthoesters

…, R Penczek, N Kuźnik, JG Małecki, M Matlengiewicz

Index: Krompiec, Stanislaw; Penczek, Robert; Kuznik, Nikodem; Malecki, Jan Grzegorz; Matlengiewicz, Marek Tetrahedron Letters, 2007 , vol. 48, # 1 p. 137 - 140

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Citation Number: 8

Abstract

Addition of alcohols and phenols to O-allyl compounds (allyl ethers and acrolein acetals), catalyzed by [RuCl2 (PPh3) 3], was examined. Intramolecular addition of an OH group, leading to the formation of cyclic acetals and orthoesters, was also investigated. As a result, a new, selective and convenient method for the synthesis of symmetrical and unsymmetrical (mixed) acetals and orthoesters was developed.

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