EPR and spin-trapping investigation of free radicals from the reaction of 4-methoxybenzenediazonium tetrafluoroborate with melanin and melanin precursors

KJ Reszka, CF Chignell

Index: Reszka, Krzysztof J.; Chignell, Colin F. Journal of the American Chemical Society, 1993 , vol. 115, # 17 p. 7752 - 7760

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Citation Number: 40

Abstract

Abstract: The interaction of synthetic DOPA melanin (DM) and its precursors (catechols and phenols) with 4-methoxybenzenediazonium tetrafluoroborate (4-MeO-PhNzBF4) has been studied using EPR spectroscopy and the spin-trapping technique. We found that DM, catechol, 3, 4-dihydroxybenzoic acid, 3, 4-dihydroxyhydrocinnamic acid, 3, 4- dihydroxyphenylalanine, and 6-hydroxydopamine all react with 4-MeO-PhNz+ through a ...