Tetrahedron letters

A concise enantioselective synthesis of allylamines and N-boc-β-amino acids

…, M Canas, M Poch, A Moyano, MA Pericàs, A Riera

Index: Alcon, Montserrat; Canas, Marc; Poch, Marta; Moyano, Albert; Pericas, Miquel A.; Riera, Antoni Tetrahedron Letters, 1994 , vol. 35, # 10 p. 1589 - 1592

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Citation Number: 40

Abstract

Abstract A new and efficient enantioselective synthesis of allylamines and N-Boc-β-amino acids has been developed. Starting from enantiomerically enriched N-diphenylmethyl-3- amino-1, 2-diols, allylamines are easily obtained by a Corey-Hopkins deoxygenative protocol. After a change in the nitrogen protecting group, the resulting N-Boc allylamines are converted into β-amino acids by hydroboration with 9-BBN followed by oxidation with PDC ...

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