Pharmaceutical Chemistry Journal

Reaction of l-(p-nitrophenyl)-2-acetylamino-l, 3-propanediol with sodium hypochlorite

VP Zhestkov, VG Voronin, YN Portnov

Index: Zhestkov, V. P.; Voronin, V. G.; Portnov, Yu. N. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 657 - 660 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1090 - 1093

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Abstract

At one of the conclusive stages in the synthesis of the levomycetin antibiotic, a racemic mixture of RIR 2-and StS2-1-(p-nitrophenyl)-2-amino-l, 3-propanediols is formed, but only the R: R2-isomer is used for the preparation of the biologically active compound. Equal