Synthesis and reactivities of a novel flavoenzyme model, 5-deazaflavin with C 2-symmetry

R Yanada, Y Yoneda, M Yazaki, N Mimura, T Taga…

Index: Yanada, Reiko; Yoneda, Yoshiyuki; Yazaki, Mikako; Mimura, Norio; Taga, Tooru; Yoneda, Fumio; Yanada, Kazuo Tetrahedron Asymmetry, 1997 , vol. 8, # 14 p. 2319 - 2323

Full Text: HTML

Citation Number: 1

Abstract

The title model compound represents a redox property of the active site of flavoenzymes and an environmental effect of the apoproteins. Its stereostructure was elucidated by 1H-NMR spectra and energy minimum calculations. The stereoselectivity of this model was observed during the reaction with Me2PNPH, as NAD (P) H model.

Related Articles:

Microwave-assisted synthesis of 3-aryl-pyrimido [5, 4-e][1, 2, 4] triazine-5, 7 (1H, 6H)-dione libraries: derivatives of toxoflavin

[Todorovic, Nick; Giacomelli, Andrew; Hassell, John A.; Frampton, Christopher S.; Capretta, Alfredo Tetrahedron Letters, 2010 , vol. 51, # 46 p. 6037 - 6040]

Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin–cholestane hybrid compounds

[Shrestha, Ajaya R.; Shindo, Takashi; Ashida, Noriyuki; Nagamatsu, Tomohisa Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 18 p. 8685 - 8696]

More Articles...