Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor

TA Lyle, Z Chen, SD Appleby, RM Freidinger…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 1 p. 67 - 72

Full Text: HTML

Citation Number: 41

Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 7, Issue 1, 7 January 1997, Pages 67–72. ... b Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486 USA; c Department of Molecular Design & Diversity, and Merck Research Laboratories, West ...

Related Articles:

Structure–activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity

[Bioorganic and Medicinal Chemistry, , vol. 14, # 24 p. 8467 - 8487]

Structure–activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity

[Bioorganic and Medicinal Chemistry, , vol. 14, # 24 p. 8467 - 8487]

More Articles...