1-[1-[2-[(3-chlorobenzyl) oxy] phenyl] vinyl]-1H-imidazole hydrochloride, a new potent antifungal agent

…, H Matsumoto, Y Hamada, M Takehara…

Index: Ogata; Matsumoto; Hamada; Takehara; Tawara Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 768 - 770

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Citation Number: 39

Abstract

Figure 1. Effect of 1. HCl and other imidazole antimycotics on viability of C. albicans IF0 1060 in yeast nitrogen base broth with L-asparagine and glucose. Drugs were added to cultures 3 h after the start of incubation in the indicated concentrations of micrograms per milliliter. of Cryptococcus neoformans and one of Torulopsis glabrata) required moderate MIC values of 10 to 80 pg/mL for inhibition.