Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann− Pick type C disease therapeutics

…, FR Maxfield, O Wiest, P Helquist

Index: Munno, Angela De; Bertini, Vincenzo; Picci, Nevio Heterocycles, 1986 , vol. 24, # 4 p. 1131 - 1136

Full Text: HTML

Citation Number: 34

Abstract

... Volume: Page ... 5. Consequently, we set out to find optimal conditions with which to conduct the substitution, using thiadiazole 4 as the ... By use of this modified protocol, acetophenone and propiophenone reacted well and provided 23 and 24, respectively, in good ...