Syntheses of macrocyclic bisbibenzyls on solid support

A Speicher, T Backes, S Grosse

Index: Speicher, Andreas; Backes, Timo; Grosse, Stefan Tetrahedron, 2005 , vol. 61, # 49 p. 11692 - 11696

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Citation Number: 26

Abstract

We describe a route for the polymer supported total synthesis of the cyclic bisbibenzyls of the isoplagiochin type found in liverworts. TentaGel® resins were used as solid support for a sequence involving Suzuki, Wittig and hydrogenation protocols. The polymer linked intermediates could be characterized by HR-MAS NMR. This route is to be extended to the synthesis of small libraries of differently halogenated derivatives.