Full Functionalization of the 7??Azaindole Scaffold by Selective Metalation and Sulfoxide/Magnesium Exchange

NM Barl, E Sansiaume??Dagousset…

Index: Barl, Nadja M.; Sansiaume-Dagousset, Elodie; Karaghiosoff, Konstantin; Knochel, Paul Angewandte Chemie - International Edition, 2013 , vol. 52, # 38 p. 10093 - 10096 Angew. Chem., 2013 , vol. 52, # 38 p. 10093 - 10096,4

Full Text: HTML

Citation Number: 18

Abstract

Azaindoles are valuable targets in the pharmaceutical and agrochemical industries due to their interesting cytotoxic activity.[1] 7-Azaindole derivatives in particular have found applications as luminescent molecules [2] and ligands.[3] Thus, synthetic methods for the simple construction and specific functionalization of such N-heterocycles are indispensable. So far, the Fischer [4, 5] and Larock [6] indole syntheses have been applied for preparing ...