Synthesis of an anthrose derivative and production of polyclonal antibodies for the detection of anthrax spores

…, H Volland, C Créminon, F Djedaïni-Pilard

Index: Dhenin, Sandrine G.Y.; Moreau, Vincent; Morel, Nathalie; Nevers, Marie-Claire; Volland, Herve; Creminon, Christophe; Djedaini-Pilard, Florence Carbohydrate Research, 2008 , vol. 343, # 12 p. 2101 - 2110

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Citation Number: 27

Abstract

A straightforward synthesis of a derivative of anthrose, the non-reducing terminal fragment of the antigenic tetrasaccharide from Bacillus anthracis, was achieved starting from d- galactose. This hapten is able to induce a highly specific and sensitive immune response in rabbit when attached to a carrier protein.