Some anticonvulsant agents derived from 1, 3-propanediols

BJ Ludwig, EC Piech

Index: Ludwig; Piech Journal of the American Chemical Society, 1951 , vol. 73, p. 5779

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Citation Number: 88

Abstract

The anticonvulsant properties of 2, 2-disubstituted-1, 3-propanediols, a class of compounds bearing little structural similarity to the accepted anticonvulsants, have recently been described.'Pharmacological studies on 2, Z-diethyl-lJ3-propanediolI2 one of the more active members of this series, indicated that this compound had a powerful but short anticonvulsant action. It was also found that the action of certain of its esters was of longer duration than ...