A concise asymmetric synthesis of the seco-acid of erythronolide B

SF Martin, GJ Pacofsky, RP Gist…

Index: Martin, Stephen F.; Pacofsky, Gregory J.; Gist, Ricky P.; Lee, Wen-Cherng Journal of the American Chemical Society, 1989 , vol. 111, # 19 p. 7634 - 7636

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Citation Number: 25

Abstract

In an effort to clarify the question of malonyl ligand conformation, the unusual spectroscopic data, and the mode of lithium cation interaction with the transition metal ligands, an X-ray diffraction study was performed on 4.4 Figure 1 shows the orientation of the CF3S03-and Li+ ions in relation to the dirhenium backbone of the molecule. The arrangement of oxygen atoms around the Li+ ion is tetrahedral, with two oxygen atoms provided by the malonyl ...