Starburst conjugates of proteins with carbon-chain polymers containing low molecular biologically active compounds: Synthesis and immunogenicity

…, GA Pankova, IN Nikonova, NG Antonov

Index: Vlasov; Pankova; Nikonova; Antonov Russian Journal of Bioorganic Chemistry, 2003 , vol. 29, # 1 p. 33 - 42

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Citation Number: 3

Abstract

Abstract The synthesis of starburst polymer–protein conjugates on the basis of bovine serum albumin and horseradish peroxidase was performed with the aim to study the possibilities of regulation of the immune response against the components of the conjugates. These polymers had one-point binding between the protein and the modifying carbon-chain polymer that contained 1-vinyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (a ...