Journal of medicinal chemistry

Aminoalkyldibenzo [a, e] cyclopropa [c] cycloheptene derivatives. Series of potent antidepressants

WE Coyne, JW Cusic

Index: Coyne,N.E.; Cusic,J.W. Journal of Medicinal Chemistry, 1974 , vol. 17, p. 72 - 75

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Citation Number: 7

Abstract

Results Protriptyline was chosen as the reference standard because it was the most potent tricyclic tested on a milligram per kilogram basis for reversing the hypothermia in mice caused by reserpine. The results of 6a, 6b, and 12a (as the phosphate salts) for both ip and ig administration