Bis (1 H-2-indolyl) methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase

S Mahboobi, S Teller, H Pongratz…

Index: Gazzetta Chimica Italiana, , vol. 85, p. 51,54 Journal of the Chemical Society, , p. 3426,3429

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Citation Number: 71

Abstract

... Volume: Page ... For preparation of the N-alkylated and benzylated species 77−85, compound 11 was reacted with the respective alkyl- and benzyl halides (Scheme 4 ... Potency is slightly lowered in substituted phenyl derivatives (IC 50 of 60 < 61 < 69 < 56 < 51 < 64 ...

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