Journal of Heterocyclic Chemistry

Synthesis and antimicrobial activities of new 4, 6??diaryl??4, 5??dihydro??3??hydroxy??2H??indazoles

P Amutha, S Nagarajan

Index: Amutha, Parasuraman; Nagarajan, Samuthira Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 428 - 432

Full Text: HTML

Citation Number: 5

Abstract

Abstract A series of new 4, 6-diaryl-4, 5-dihydro-3-hydroxy-2H-indazoles 5a, 5b, 5c, 5d, 5e, 5f, 5g, 5h, 5i, 5j, 5k were synthesized by the cyclization of ethyl 2-oxo-4, 6-diarylcyclohex-3- ene carboxylates 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j, 4k. The compounds were characterized by IR, 1 H NMR, 13 C NMR, 2D NMR, and elemental analysis. The synthesized compounds were evaluated for in vitro antibacterial and antifungal activities against Staphylococcus ...